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2017 Jul;67(7):1127

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Inactivation of one SOD allele in transgenic (Tg2576) mouse model of AD has shown to bolster the accumulation of Aβ plaques (Murakami et al., 2011) while overexpression of SOD in mice has shown to reduce the plaque formation and lower cognitive deficits (Massaad et al., 2009)