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When It Is Still Usable Discard immediately if: The solution is cloudy, discolored, or contains visible particles The vial has been at room temperature for over 24 hours The vial has an unusual or foul smell More than 30 days have passed since reconstitution (with bac water) More than 48 hours have passed since reconstitution (with sterile water) The solution froze at any point, even partially Likely still usable if: The solution is clear and colorless The vial has been consistently refrigerated You are within the recommended shelf life window A brief room-temperature exposure (under 4 hours) occurred once When in doubt, discard

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While a provider should confirm a deficiency first, certain groups tend to benefit most from a weekly schedule during active treatment