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Figure 2 3.1 Fluoride As widely documented, fluoride combats dental caries through three mechanisms: inhibiting demineralization, promoting remineralization, and suppressing bacterial metabolism ( Calcium fluoride (CaF 2 ) nanoparticles (average 58 nm), synthesized via spray-drying and incorporated into resin matrices, exhibit excellent biocompatibility and significantly enhanced F − release capacity that remains stable over repeated recharging cycles (Yi et al., 2019)
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