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168 A large meta-analysis of 65 randomized controlled trials with 7,887 hypertensive subjects found folic acid plus blood pressure-lowering medication was more effective than medication alone for lowering blood pressure, lowering homocysteine levels, and reducing risk of cardiovascular events and stroke by 13% compared with control groups

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However, glycogen is not only an emergency fuel, but is also continuously synthesized and degraded during normal brain activity (Dienel et al