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Furthermore, lonafarnib, a farnesyltransferase inhibitor preventing the accumulation of mutant lamin A in the nuclear membrane, improved the life span, cardiovascular degeneration, skeletal rigidity, and hearing of patients with Hutchinson-Gilford progeria syndrome but did not ameliorate sclerodermoid and alopecic skin features (154)
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Growth hormone plays an important role in: muscle development fat metabolism tissue repair This is one reason growth hormone peptides are commonly studied in regenerative medicine
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