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SCLC is vulnerable to the induction of ferroptotic cell death To validate whether SCLC was vulnerable to ferroptotic cell death in general, murine SCLC cells were treated with the GPX4 small molecule inhibitor RSL3, known to trigger ferroptosis 28 with or without the lipophilic radical scavenger Ferrostatin-1 (Fer-1) shown to specifically block ferroptotic cell death 51

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