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The breakdown of hemoglobin releases a substantial quantity of iron ions, leading to significant reduction in cell viability, superoxide dismutase and glutathione levels, increased generation of reactive oxygen species, lipid peroxidation and malondialdehyde levels, as well as upregulation in the expression of ferroptosis-related proteins that induce mitochondrial ultrastructural changes

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cluster C in [16], suggested to be involved in cell structure)