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Targeting Oxysterol-Binding Protein (OSBP) as a Novel Strategy to Inhibit Herpes Simplex Virus 2 (HSV-2) Replication: First Structure-Activity Relationship Study of Antiviral Cholenamide Derivatives - ScienceDirect

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In the first enzyme reaction, methylcobalamin is used to recycle the folate cofactor 5-methyltetrahydrofolate to tetrahydrofolate thereby allowing the folate cofactor to participate in a cycle involving the biosynthesis of purines and pyrimidines