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An Injectable Alternative for Treating Uterine Fibroids | Duke Clinical and Translational Science Institute

123 Besides, oxidative stress conditions also increase the innately high IDH1 expression, and IDH1 silencing significantly enhances cell sensitivity to cancer chemotherapy, radiotherapy, and photodynamic therapy by reducing NADPH

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Although acetyl-CoA is a metabolite of fundamental importance in eukaryotic organisms, since it drives the tricarboxylic acid (TCA) cycle required for energy generation, it remains one of the most poorly studied potential targets of aspirin in the context of the latter’s antineoplastic effects 2