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Therefore, GSTπ may promote the S-glutathionylation of a wide range of proteins, and its high expression in tumor cells may be related to the aberrant oxidative stress state [96]

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256 In addition, ethanol could activate kinase CK2 to phosphorylate MATα1 at Ser114, promote its interaction with PIN1 isomerase, inhibit MATα1 localization in mitochondria, and promote ethanol-induced mitochondrial dysfunction and fat accumulation