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In particular, increased production of 2,3-dihydroxybenzoic acid and 2,5-dihydroxybenzoic acid has been reported as a marker of aspirin metabolism in inflammatory and other conditions, which is associated with increased production of hydroxyl radical formation during oxidative stress [252,253,293,294]

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3.2.3 Lipid oxidation abnormalities Furthermore, depression has been associated with the activation of innate immune responses and mild systemic inflammation (136)