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2009) used kinetic simulations to assess relative contributions of human CBS and human CSE to H 2 S production when the amounts of the two enzymes are equimolar, the substrate concentrations are near to assumed physiological levels (i.e., 0.56 mM serine, 0.10 mM Cys, 0.01 mM Hcy), and CBS is fully activated by its allosteric regulator S-adenosylmethionine
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In the last decade, in the context of therapeutic strategies against cancer, peptide-based vaccines have been evaluated in different tumor models
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