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Mechanism of Action: Dual Receptor Targeting Cagrilintide operates through a sophisticated dual receptor mechanism, functioning as both an amylin receptor agonist (targeting AMY1R, AMY2R, and AMY3R) and a calcitonin receptor (CTR) agonist

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Further work has looked at interactions with dopaminergic and serotonergic systems and at gastrointestinal mucosal models