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11:198–202 Lee WJ , Hsu HY , Wang PY : Reversible myelopathy on magnetic resonance imaging due to cobalamin deficiency

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At this time, bubbles may be observed directly crossing a septal defect, or else a patent foramen ovale may be opened temporarily by asking the patient to perform the Valsalva maneuver while the bubbles are crossing through the right heart – an action which will open the foramen flap and show bubbles passing into the left heart

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