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[DOI] [PMC free article] [PubMed] [Google Scholar] 148.Dohgu S., Takata F., Matsumoto J., Kimura I., Yamauchi A., Kataoka Y

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Studies using animal models found that increasing the iron content in the brain can exacerbate the aggregation of Aβ and increase the death of nerve cells in the affected brain region (97), while the use of iron-chelating agents to reduce the iron level in the brain can significantly improve the symptoms of AD (100)