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[94] Clinical Diagnosis: Repeated sun exposure promotes the development of recurrent blisters and erosions, with secondary infections that may result in severe scarring, sclerodermatous change, and deformities of the hand.[95] Sclerodactyly, osteolysis and shortening of the phalanges, and progressive joint deformities can occur as well

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Copper toxicity is a theoretical concern with high-dose systemic GHK-Cu