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In a phase 2 study, comparing the results of the empagliflozin arm to the control arm showed a significant improvement in the electrophysiological studies and a significant decrease in the pain score and the mean serum levels of neuron-specific enolase and malondialdehyde in patients with DPN

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In the β3-KO and WT groups, male mice aged 12–14 weeks were divided into three subgroups including: saline control, AOD9604 administered at a dose of 250 µg/kg/day, and hGH administered at a dose of 1 mg/kg/day

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