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These conditions often involve chronic low-grade inflammation, cartilage degradation, and synovial fluid changes
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3T3-F44 2A pre-adipocytes treated with BMP-2 showed a decrease in insulin-induced lipid accumulation (Skillington et al., 2002), but BMP-7 increased the differentiation of 3T3-L1 pre-adipocytes, demonstrating the contradictory roles of BMPs in adipogenesis (Rebbapragada et al., 2003
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