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CYP-derived HETEs and cancer 20-HETE has long been implicated in the proliferation of tumor cells and endothelial cells, often invoking the participation of growth factors, such as VEGF, epidermal growth factor (EGF), fibroblast growth factor (FGF), or platelet-derived growth factor (PDGF)

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Depends on pigmentation level and goals—usually 6–12 sessions for best results