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Gallbladder-related events including cholelithiasis (gallstones) and cholecystitis (gallbladder inflammation) are potential concerns with rapid weight loss from any cause, and these have been reported in some participants receiving cagrilintide, consistent with weight loss-associated risks seen with other obesity medications and bariatric surgery

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Single-cell ATAC-Seq reveals cell type-specific transcriptional regulation and unique chromatin accessibility in human spermatogenesis