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implications for initiation of mammary tumors

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Gunn rat liver sample preparation Hyperbilirubinaemic Gunn rats (20 in total, 9 males and 11 females), homozygous for a mutation in UGT1A1 , and the same number of normobilirubinaemic Wistar rats, heterozygous for a mutation in UGT1A1 , were obtained from Charles University in Prague (Prague, Czech Republic) and acclimatized in the breeding facility of the Medical University of Vienna (Himberg, Austria)