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Journal of Molecular Medicine (2017) Model system Chick chorioallantoic membrane assay, endothelial cell culture, rat hind-limb ischemia model Conditions Vessel density, laser-Doppler perfusion, VEGFR2 expression and endocytosis, Akt and eNOS phosphorylation, tube formation Reported finding Vessel density increased in vivo and in vitro, VEGFR2 expression rose, receptor internalization was promoted in endothelial cells, and the VEGFR2-Akt-eNOS signaling axis was activated with increased endothelial tube formation
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