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Twenty new mutations implicated in rare genetic disease

KARs, however, have received less attention, despite their significant role in neuronal development, synaptic depolarization, intrinsic cellular excitability, and homeostatic synaptic plasticity gatekeeping (Valbuena and Lerma, 2021)

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Various dietary interventions, including carbohydrate, fat and, more recently, amino acid restriction, have been explored to combat this epidemic 3,4,5,6