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In hypercholesteremic rats, lycopene administration (50 mg/kg) significantly decreased low-density lipoprotein-cholesterol (LDL), total cholesterol (TC), thiobarbituric acid reactive substances (TBARS), very low-density lipoprotein-cholesterol (VLDL), triglycerides (TG), and increased high-density lipoprotein-cholesterol (HDL) level [59,97]