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Insulinepen vial Not applicable, since this product is a device (vial) designed for administration and storage of peptides in research settings, rather than a biochemical agent

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In the heterotetrameric structure of Bacillus (Geobacillus) stearothermophilus pyruvate dehydrogenase, a Gram-positive bacterium, each thiamine pyrophosphate molecule binds between the N-terminal domains of an α and a β subunit, at the end of a funnel-shaped channel ≈ 21 Å deep that leads to the active site