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105 injected tumorigenic β-catenin and MET into β-catenin-deficient livers to induce cancer, and unexpectedly found that Sox9 + cells with stem cell properties expanded inflammatory, upregulated cytokines, and several pro-tumorigenic pathways such as Akt, Erk, and Wnt/β-catenin were also enhanced to exacerbate HCC progression
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The receiver operating characteristic curve was used to define the cut-off point
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