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fructosamine or glycated albumin may also be considered as short-term alternatives when HbA1c is unreliable Document the timing of B12 treatment initiation in the patient's records to contextualise any HbA1c results obtained during this period This approach ensures that clinical decisions regarding diabetes diagnosis or medication adjustment are based on accurate data rather than a transiently distorted HbA1c result

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This sets the stage for neuroinflammation, which amplifies oxidative stress and excitotoxicity, as discussed in subsequent sections