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Dynamic Transcriptomic and Cellular Remodeling Underlie Cuprizone-Induced Demyelination and Endogenous Repair in the CNS

Glutamate is converted to α-KG both via GLUD1, generating glutamate-derived nitrogen as ammonia, and via aminotransferases, which transfer nitrogen from glutamate to α-KG to produce other NEAAs

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Recent studies in mice have also shown that the repeated administration of insulin or GAD peptides, including the B9–23 peptide, can induce lethal anaphylactic responses (16, 17)