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21 The authors concluded that POTS is “rarely reported following HPV vaccination” and that their review “did not detect any unusual or unexpected reporting patterns that would suggest a safety problem.” 21 In 2020, Barboi et al conducted a comprehensive literature review to evaluate the potential connection between HPV vaccination and the development of autonomic disorders such as POTS, dysautonomia, chronic fatigue, complex regional pain syndrome, and postural tachycardia syndrome
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