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Obesity and metabolic syndrome Metabolic syndrome Metabolic syndrome is a cluster of conditions that significantly increases the risk for several secondary diseases, notably cardiovascular disease, type 2 diabetes, and nonalcoholic fatty liver

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In diabetes-associated PAD, stenotic lesions predominantly affect distal arteries, such as the popliteal artery and the anterior tibial, posterior tibial and peroneal arteries, in contrast to the more proximal lesions seen in nondiabetic individuals

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