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Efficacy and safety of intravenous induction and subcutaneous maintenance therapy with guselkumab for patients with Crohn's disease (GALAXI-2 and GALAXI-3): 48-week results from two phase 3, randomised, placebo and active comparator-controlled, double ...

The body composition changes take months because they require sustained IGF-1 elevation to drive lipolysis, protein synthesis, and collagen production at scale

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