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Dysbiosis can affect the kynurenine pathway of tryptophan metabolism, leading to an imbalance in neuroactive metabolites that influence mood, cognition, and pain perception (He et al., 2023)
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Copper is a cofactor for lysyl oxidase (the enzyme that crosslinks collagen and elastin), superoxide dismutase (a critical antioxidant enzyme), and numerous other copper-dependent enzymes involved in tissue maintenance