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The recombination events that did occur in the ruvA mutant during infection of wild-type mice were not only less frequent but also used fewer silent loci as templates, indicating that the fine-scale segmental gene conversion that generates multiple changes of few amino acids in the parental bacteria is not active in the mutant

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Confirm the timing with your healthcare provider if you have missed multiple injections, stopped treatment for an extended period, or are uncertain about restarting