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Concurrently, ACC inhibition reduces inflammatory macrophage recruitment through blockade of chemokine receptors CCR2/CCR5 (e.g., via cenicriviroc), thereby attenuating pro-inflammatory cytokine production in pulmonary niches (Tacke and Weiskirchen, 2018)

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For mammary fat pad injections, 2 × 10 6 cells were resuspended in 50% Matrigel (Corning) and injected (50-μl volume) into female mammary fat pads