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The main properties influencing the substrate affinity are: the presence of the charged amino and carboxyl groups, L-configuration (not D-) of the α-carbon, net neutral charge, size and, to a lesser extent, hydrophobicity of the side-chains (Yamashita et al., 2005)
![PDF] Clinical observation on tranexamic acid combined with reduced glutathione for the treatment of chloasma](https://figures.semanticscholar.org/83ea9a78414f20b1af8b6de501f6baa92c1cacae/3-Table3-1.png)
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