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Greater levels of anti-cagrilintide antibodies were detected with higher doses of cagrilintide, but very few were neutralizing against cagrilintide or native amylin

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In experimental models with hepatic steatosis induced by a fat-rich diet, a diminution was found of transcription due to the diminished levels of mRNA of the components AMPK-PGC-1α, NRF-2, and β-ATP synthase [52]

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