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The STEP 1 clinical trial showed that participants began seeing measurable weight reduction within the first 4 to 8 weeks of treatment
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The Phase 2 trial reference point The Phase 2 retatrutide trial (Jastreboff et al., New England Journal of Medicine 2023) enrolled 338 adults across placebo and retatrutide arms at 1, 4, 8, and 12 mg weekly
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