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Homing peptides capable of selectively delivering many kinds of molecules have been identified and hold great promise for the development of less toxic therapeutic methods to treat several diseases.7, 8, 9, 10 These homing peptides usually consist of 3–12 amino acids with exceptionally strong binding affinity and selectivity for their target molecules.11, 12 These peptides can be screened using phage display technology, which is an efficient method for searching a peptide library in order to identify a sequence that specifically binds to a target molecule.13, 14 The method can be used both in vitro and in vivo ;15, 16 the latter approach allows the identification of homing peptides that target the surface of cells in their physiological microenvironment.12, 16, 17, 18, 19, 20, 21 Combining these homing peptides with an anticancer agent promotes more effective tumor regression than use of the anticancer agent alone
