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These compounds penetrate the BBB in sufficient quantity to facilitate memory consolidation and retrieval in aged rats, and the scopolamine-induced amnesic rat model of AD, as measured employing the Morris water maze task of spatial memory [80]
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The Mediterranean Diet and Alzheimer’s Disease The first clinical study on the MEDiet and the risk of AD was published in 2006 by Scarmeas et al., where the authors concluded that a higher adherence to the MEDiet was associated with a reduction in the risk of AD [79]
