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Certain treatments like NAD+ (the oxidized form of coenzyme nicotinamide adenine dinucleotide) and glutathione require an initial series of frequent doses to build a durable physiological baseline
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799 Similarly, rosiglitazone, another PPAR-γ agonist, enhances Frataxin levels in Frataxin-deficient dorsal root ganglia neurons, boosting mitochondrial biogenesis, function, calcium homeostasis, and cell survival
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