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They include: loratadine (Claritin, other brands) fexofenadine (Allegra, other brands) cetirizine (Zyrtec, other brands) desloratadine (Clarinex, other brands) levocetirizine (Xyzal) Chronic hives that don’t respond to over-the-counter antihistamines may be treated with prescription medications such as: omalizumab, an IgG monoclonal antibody cyclosporine Before exploring alternative therapy options, it’s important to note that more research is necessary to determine whether these treatments are effective

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It may take several days or even weeks to feel a difference