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Furthermore, combining ferroptosis sensitization with T-cell-based immunotherapies, such as chimeric antigen receptor (CAR) T cells, 57 represents a particularly promising strategy

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By international agreement, standardized methods have been used to characterize these enzyme variants, which differ on the basis of biochemical properties such as kinetic activity, electrophoretic mobility, the Michaelis constant for its substrate glucose-6-phosphate and cofactor NADP, the ability to utilize different substrate analogues, heat stability, and pH optima