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109 During adipogenesis berberine affects PPARγ transcriptional activity, mRNA, and protein levels in 3T3-L1 cells by interfering with the C/EBPβ signal

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A double-blind, randomized, placebo-controlled trial in 130 PCOS patients showed the combination of letrozole plus 1,200 mg NAC per day resulted in more follicles greater than 18 mm in diameter (a size associated with greater likelihood of ovulation) after five days than letrozole alone or placebo