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Retatrutide has not been compared head-to-head with earlier GLP-1 medications in any clinical trials, although there is an ongoing trial called TRIUMPH-5, which is comparing it with tirzepatide

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For these features, Tα1 was used as an adjuvant or immunotherapeutic agent to treat disparate human diseases, including viral infections, immunodeficiencies and malignancies (Romani et al., 2012)