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Abbreviations CBS cystathionine β-synthase CSE cystathionine γ-lyase DC dendritic cell Hcy homocysteine HHcy hyperhomocysteinaemia MMP matrix metalloproteinase MTX methotrexate NAC N-acetyl cysteine NET neutrophil extracellular trap NF-κB nuclear factor κB NO nitric oxide OS Oxidative stress PASI psoriasis area and severity index PsA psoriatic arthritis RA rheumatoid arthritis ROS reactive oxygen species SAH S-adenosyl-L-homocysteine SAM S-adenosyl-L-methionine SFN Sulforaphane Treg regulatory T cell VEGF vascular endothelial growth factor Author Contribution Xiran Lin designed and wrote the manuscript

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