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Contraindications and cautions [9]: Drug interactions: Colchicine, aminoglycosides, certain anticonvulsants (e.g., Phenytoin, Phenobarbital, Primidone), para-aminosalicylic acid or excessive alcohol intake may impair the absorption of vitamin B12
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For example, ethanol will increase the activity of and stabilize CYP2E1, causing increased activity in the pathway from acetaminophen to NAPQI
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![Figure, Histopathology of Vitamin A Deficiency...] - StatPearls](https://www.ncbi.nlm.nih.gov/books/NBK613280/bin/vitamin__A__deficiency__histopathology.jpg)
