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4,1-benzothiazoles are non-calcium antagonist drugs that reduce calcium levels in neurons by modulating mitochondria (Viejo et al., 2021)

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The permeability study demonstrated enhanced BBB (in vitro model) permeability mediated by lactoferrin receptor-targeted transcytosis, showing a 2.7-fold increase in fluorescence intensity for lactoferrin-conjugated nanoparticles compared to non-functionalized ones