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Additionally, tobacco consumption changes the composition of the microbiota in the gut in a way that mitigates intestinal inflammation, and then leads to less misfolding of the protein α -Syn in enteric nerves, reducing the risk of PD by minimizing propagation of the protein aggregates to the central nervous system (CNS) (Derkinderen et al., 2014)
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Higher peak levels: Faster absorption produces higher peak blood concentrations, which may be desirable for some research protocols
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