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Over time, however, researchers came to understand that amylin has a distinct and important set of functions in regulating metabolism and food intake

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Moreover, goldenseal can also inhibit the cytochrome P450 isoforms, including CYP1A2, CYP2D6, CYP2E1, and CYP3A, and the IC 50 values were 15.7, 7.4, 4.3, and 52.1 µg/ml in rats, respectively

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