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Polyp behavior has been a common endpoint reported in numerous coral studies with other chemical contaminants, but the implication of this response, especially at the population level, is unknown and further studies should investigate the long-term repercussions of this to fully understand its utility in determining impact (Mitchelmore et al., 2021)

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Various other centrally acting appetite suppressants, including stimulants and serotonergic drugs (such as dexfenfluramine, fenfluramine, sibutramine, and rimonabant), have been used in the management of obesity but have been withdrawn or are no longer recommended due to serious safety concerns or their addictive potential